photo-liliane

Liliane BOREL

 

Director of research at the CNRS (French National Research Center)

Sensory & Cognitive Neurosciences Lab

Sensory & Cognitive Rehabilitation Team

Tel : 33 (0) 4 13 55 08 73

E-mail : liliane.borel@univ-amu.fr

 

Research Topics

Vestibular functions and their compensation: balance and gait, perception, orientation and spatial representation

Interactions and compensations between sensorimotor and cognitive functions

Factors affecting sensory and cognitive functions and their interaction: stereotype threat and mindfulness disposition

 

Current Research

– Adaptive processes after vestibular loss (Body and extrapersonal space representation – Mental imagery)

– Similarity between vestibular loss and spatial neglect

– Anxiety and control of postural balance

– Cognitive influences in balance control (Elderly, Patients with vestibular loss, Patients with brain trauma)

– Balance and cognition: interaction and contribution to rehabilitation

– Consequences of stereotype threat on balance abilities, cognitive functions and their interactions?

– Consequences of mindfulness on balance abilities, cognitive functions and their interactions? (currently in development)

– Cognitive and sensory rehabilitation : differential effects and underlying mechanisms of action

 

– Transfer of research towards clinical practice and rehabilitation programs

 

 

Publications

Borel L, Ribot-Ciscar E (2016) Improving postural control by applying mechanical noise to ankle muscle tendons. Exp Brain Res 234:2305–2314

Bringoux L, Scotto Di Cesare C, Borel L, Macaluso Th, Sarlegna F (2016) Do visual and vestibular inputs compensate for somatosensory loss in the perception of spatial orientation? Insights from a deafferented patient. Frontiers in Hum Neurosci 10:181. doi: 10.3389/fnhum.2016.00181

Deroualle D, Borel L, Devèze A, Lopez C (2015) Changing perspective: the role of vestibular signals. Neuropsychologia. http://dx.doi.org/10.1016/j.neuropsychologia.2015.08.022

Devèze A, Montava M, Lopez C, Lacour M, Magnan J, Borel L (2015) Vestibular compensation following vestibular neurotomy. Eur Ann Otorhinolaryngol Head and Neck diseases 132: 197–203.

Borel L, Redon-Zouiteni C, Cauvin P, Dumitrescu M, Devèze A, Magnan J, Péruch P (2014) Unilateral vestibular loss impairs external space representation. PLoS ONE 9(2): e88576. doi:10.1371/journal.pone.0088576

Borel L, Alescio-Lautier B (2014) Posture and cognition in the elderly: interaction and contribution to the rehabilitation strategies. [Review]. Neurophysiol Clin 44(1):95-107.

Saj A, Cojan Y, Musel B, Jacques Honoré J, Borel L, Vuilleumier P (2014) Functional neuro-anatomy of egocentric representation. Neurophysiol Clin 44(1):33-40.

Paillard T, Borel L (2013) Unilateral and bilateral fatiguing contractions similarly alter postural stability but differently modify postural position. Human Movement Science 32: 353–362.

Tremblay L, Kennedy A, Paleressompoulle D, Borel L, Mouchnino L, Blouin J (2013) Biases in the perception of self-motion during whole-body angular acceleration and deceleration. Frontiers in Integrative Neurosciences 7:90.

Saj A, Honoré J, Bernard L, Devèze A, Magnan J, Borel L (2013) Where is straight ahead to a patient with unilateral vestibular loss? Cortex 49:1219-1228.

Young LR, Bernard-Demanze L, Dumitrescu M, Magnan J, Borel L, Lacour M (2012) Does fear of falling influence control of posture? A comparative study in healthy subjects and compensated unilateral vestibular loss patients. J Vest Res 22(2):129-38.

Péruch P, Lopez C, Redon-Zouiteni C, Escoffier G, Zeitoun A, Sanjuan M, Arnaud Devèze A, Magnan J, Borel L (2011) Vestibular information is necessary for maintaining metric properties of representational space: Evidence from mental imagery. Neuropsychologia 49: 3136– 3144.

Redon C, Lopez C, Bernard-Demanze L, Dumitrescu M, Magnan J, Lacour M, Borel L (2011) Betahistine treatment improves the recovery of static symptoms in patients with unilateral vestibular loss. J Clin Pharmacol 51: 538-48

Paillard T, Chaubet V, Maitre J, Dumitrescu M, Borel L (2010) Disturbance of contralateral unipedal postural control after stimulated and voluntary contractions of the ipsilateral limb. Neurosci Res 68(4): 301-6

Paillard T, Maitre J, Chaubet V, Borel L (2010) Stimulated and voluntary fatiguing contractions of quadriceps femoris differently disturb postural control. Neurosci Lett. 477(1): 48-51.

Paillard T, Margnes E, Maitre J, Chaubet V, François Y, Jully JL, Gonzalez G, Borel L (2009) Electrical stimulation superimposed onto voluntary muscular contraction reduces deterioration of both postural control and quadriceps femoris muscle strength. Neuroscience 165 (4): 1471-5

Bernard-Demanze L, Dumitrescu M, Jimeno P, Borel L, Lacour M (2009) Age-related changes in posture control are differentially affected by postural and cognitive tasks complexity. Current Aging Sciences. 2: 135-149

Tardieu C, Dumitrescu M, Giraudeau A, Blanc JL, Cheynet F, Borel L (2009) Dental occlusion and postural control in adult. Neurosci Lett 450: 221–224

Lacour M, Dutheil S, Lopez C, Tighilet B, Borel L (2009) Tell me your vestibular deficit, and I’ll tell you how you’ll compensate [Review]. Ann NY Acad Sci 1164: 268–278.

Borel L, Lopez C, Péruch P, Lacour M (2008) Vestibular syndrome: a change in internal spatial representation. [Review]. Neurophysiol Clin 38: 375-389

Lopez C, Lacour M, Léonard J, Magnan J, Borel L (2008) How body position changes visual vertical perception after unilateral vestibular loss. Neuropsychologia 46: 2435–2440

Lopez C, Lacour M, El Ahmadi AS, Magnan J, Borel L (2007) Changes of visual vertical perception: a long-term sign of unilateral and bilateral vestibular loss. Neuropsychologia 45: 2025–2037

Lopez C, Lacour M, Magnan J, Borel L (2006) Visual field dependence-independence before and after unilateral vestibular loss. NeuroReport 17 (8): 797-803

Péruch P, Borel L, Magnan J, Lacour M (2005) Direction and distance deficits in path integration after unilateral vestibular loss depend on task complexity. Cogn Brain Res 25: 862-872

Lopez, Borel L, Magnan J, Lacour M (2005) Torsional optokinetic nystagmus after unilateral vestibular loss: asymmetrical changes and compensation. Brain 128: 1511-1524

Borel L, Harlay F, Lopez C, Magnan J, Chays A, Lacour M (2004) Walking performance of vestibular-defective patients before and after unilateral vestibular neurotomy. Behav Brain Res 150 (1-2): 191-200

Bouët V, Borel L, Harlay F, Gahery Y, Lacour M (2004) Kinematics of treadmill locomotion in rats conceived, born and reared in a hypergravity field (2g). Adaptation to 1 g. Behav Brain Res 150 (1-2): 207-216

Borel L, Harlay F, Magnan J, Chays A, Lacour M (2002) Deficits and recovery of head and trunk orientation and stabilisation after unilateral vestibular loss. Brain 125: 880-894

Borel L, Harlay F, Magnan J, Chays A, Lacour M (2001) How changes in visual reference frames combine to modify body orientation in space. NeuroReport 12 (14) : 3137-3141

Péruch P, Borel L, Gaunet F, Thinus-Blanc C, Magnan J, Lacour M (1999) Spatial performance of unilateral vestibular defective patients in nonvisual versus visual navigation. J Vest Res 9: 37-47

Gustave dit Duflo S, Borel L, Harlay F, Léonard J, Lacour M (1998) Short-term changes in neck muscle and eye movement responses following unilateral vestibular neurotomy in the cat. Exp Brain Res 120: 439-449

Lacour M, Barthélémy J, Borel L, Magnan J, Xerri C, Chays A, Ouaknine M (1997) Sensory strategies in human postural control before and after unilateral vestibular neurotomy. Exp Brain Res 115: 300-310

Borel L, Le Goff B, Charade O, Berthoz A (1994) Gaze strategies during linear motion in head-free humans. J Neurophysiol 72 (5) 2451-2466

Zennou-Azogui Y, Borel L, Lacour M, Ez-zaher L, Ouaknine M (1993) Recovery of head postural control following unilateral vestibular neurectomy in the cat. Neck muscle activity and neuronal correlates in Deiters’ nuclei. Acta Oto-Laryngologica, Suppl. 509, 19p

Lacour M, Borel L (1993) Vestibular control of posture and gait. Arch Ital Biol 131 (2-3) : 81-104

Borel L, Lacour M (1992) Functional coupling of the stabilizing eye and head reflexes during horizontal and vertical linear motion in the cat. Exp Brain Res 91: 191-206

Vitte E, Borel L, Pozzo T, Perrin Ph, Freyss G (1992) Vestibular studies: current status, prospects. Ann Radiol (Paris). 1992; 35(1-2): 26-35

Lacour M, Borel L (1989) Functional coupling of the stabilizing gaze reflexes during vertical linear motion in the alert cat. Progress in Brain Res 80: 385-394

Xerri C, Barthélémy J, Borel L, Lacour M (1988) Neuronal coding of linear motion in the vestibular nuclei of the alert cat. III. Dynamic characteristics of visual-otolith interactions. Exp Brain Res 70: 299-309

Barthélémy J, Xerri C, Borel L, Lacour M (1988) Neuronal coding of linear motion in the vestibular nuclei of the alert cat. II. Response characteristics to vertical optokinetic stimulation. Exp Brain Res 70: 287-298

Xerri C, Borel L, Barthélémy J, Lacour M (1988) Synergistic interactions and functional working range of the visual and vestibular systems in postural control: neuronal correlates. [Review]. Progress in Brain Res 76: 193-203

Xerri C, Barthélémy J, Harlay F, Borel L, Lacour M (1987) Neuronal coding of linear motion in the vestibular nuclei of the alert cat. I. Response characteristics to vertical otolith stimulation. Exp Brain Res 65: 569-581

Lacour M, Borel L, Barthélémy J, Harlay F, Xerri C (1987) Dynamic properties of the vertical otolith neck reflexes in the alert cat. Exp Brain Res 65: 559-568

Professional Experience

2018-2022: Co-leader of the “Sensory and Cognitive Rehabilitation” team

2008-2011: Team Leader “Dynamics of Vestibular Functions”
Since 1992: Researcher at CNRS

 

Organization of Scientific Training

Head of the Inter-University Diploma in Clinical Posturology (Aix-Marseille University)

 

Collective Expertise

Collective expertise INSERM ordered by the Ministry of Sports. “Physical activity and falls prevention among older people”. Published on 27-11-2014. Main document: 509 pages. Electronic version: www.inserm.fr/content/download/…/Chutes ouvrage corpus-webv2.pdf

Synthesis and Recommendations: 95 pages.Electronic version: http://www.inserm.fr/espace-journalistes/activite-physique-et-prevention-des-chutes-chez-les-personnes-agees-une-expertise-collective-de-l-inserm

 

Scientific Commitees

Vice-President Research and member of the scientific council of the Francophone Society of Posture, Balance and Locomotion (SOFPEL) (Since 2015)

President of the scientific council of the Posture and Balance Association (APE) (2007-2015)

Elected member of the Specialists Commission. Groupe X Sections 64-65-69 (1995-2004 and 2007-2008)